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. 1999 Jan 4;189(1):179–186. doi: 10.1084/jem.189.1.179

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Enhanced FcγR-triggered responses of FcγRII^−/− macrophages. (A) Phagocytosis of IgG2b-coated RBCs is enhanced in FcγRII^−/−: phagocytic index is expressed as the number of RBCs ingested by 500 representative macrophages. (B) Enhanced calcium flux responses upon FcR ligation in FcγRII^−/− mice. Peritoneal macrophages were preincubated with mAb 2.4G2 before stimulation with the secondary antibody, goat anti–rat IgG mAb. Relative fluorescence indicative of intracellular Ca²⁺ is shown for wild-type (WT) and FcγRII^−/− mice.