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. 1999 Jan 4;189(1):187–194. doi: 10.1084/jem.189.1.187

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Proliferation and IFN-γ production of anticollagen lymph node cells in response to CII. (A) Lymph node cells (5 × 10⁵/well) were stimulated in vitro with 5, 50, or 100 μg/ml heat-denatured CII (dCII) for 4 d. Proliferative response was determined by uptake of [³H]TdR pulsed for the final 18 h of culturing. (B) Each of the culture supernatants at the end of the experiment in A was collected and assessed for the IFN-γ content by ELISA. **P < 0.01 compared with wild-type mice.