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. 2000 Jul 3;192(1):31–40. doi: 10.1084/jem.192.1.31

Figure 6.

Figure 6

Recipients of H2-DMα−/− grafts are efficient producers of alloantibodies. The presence and level of serum alloantibodies was determined by FACS®. (A) All three recipient groups produce nearly equal levels of alloantibodies directed against allogeneic class I 7 d after transplant. (B) Serum collected at the time of rejection from recipients of I-Aβ b/− or H2-DMα−/− grafts, ∼20 d, have an elevated level of class I–specific alloantibodies. (C) Recipient sera did not stain B cells from mice lacking MHC expression (β2m−/− × I-Aβ b/−). In B and C, data are means ± SD of serum samples from at least three animals.