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. 2004 Jan 5;199(1):91–98. doi: 10.1084/jem.20031330

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Copyright © 2004, The Rockefeller University Press

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Figure 2. — Blockade of BLyS via TACI-Ig inhibits PC survival in vivo. Approximately 6–8 wk after immunization with PE-CFA, immune mice (four mice/group) were treated with 100 μg TACI-Ig or human Ig every 3 d for a period of 2 wk. After the 2-wk period of treatment, BM, lymph node (LN), or spleen (SP) tissue samples were isolated from treated mice, and the number of αPE IgG ASCs was determined by ELISPOT analysis. Standard error was calculated between values from four independent mice for each treatment group. Data are representative of three independent experiments.