Figure 11.

Periodicity of gating perturbations in the S3–S4 linker. (A) Amino acid sequence of the S3–S4 linker in the drk1 K⁺ channel. The bar indicates the stretch used for Fourier transform analysis. (B) The power spectrum of the |ΔΔG ₀| values for this stretch, where P(ω) is plotted as a function of angular frequency (ω). The primary peak of power spectrum occurs at 104°. (C) Helical wheel diagram of these 17 residues viewed from the NH₂ terminus. Large shaded circles indicate positions with |ΔΔG ₀| > 0.5 kcal mol⁻¹ and large open circles indicate positions with |ΔΔG ₀| ≤ 0.5 kcal mol⁻¹.