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Results of Docetaxel Trials for Hormone-Refractory Prostate Cancer: SWOG 9916 and TAX 327
| SWOG 9916 | TAX 327 | |
|---|---|---|
| Medications | Docetaxel/estramustine | Docetaxel q3wk/ |
| Prednisone | ||
| Median OS (vs M/P) | 17.5 mo (15.6 mo) | 18.9 mo (16.5 mo) |
| Hazard ratio (vs M/P) | 0.8 | 0.76 |
| PSA response (vs M/P) | 50% (27%) | 45% (32%) |
| Neutropenic fever | 5% | 3% |
M/P, mitoxantrone and prednisone; OS, overall survival.
