Table 6.
Survival Analysis in EOGC
| Variable | Univariate (KM, log-rank) P value | Multivariate*
|
Comments on 10-year survival | ||
|---|---|---|---|---|---|
| P value | HR | 95% CI | |||
| Tumor size (0 to 5, 5 to 10 versus >10 cm) | 0.0002 | 0.09 | 1.1 | 1.0–1.2 | Worse in larger tumor sizes |
| Tumor site proximal versus middle versus distal | 0.01 | 0.19 | 1.2 | 0.9–1.6 | Worse in proximal |
| Tumor depth (T1, T2, T3 versus T4) | <0.0001 | 0.0002 | 2.1 | 1.4–3.1 | Worse in deepest invading tumors |
| Nodal status (N0 versus N+) | <0.0001 | 0.001 | 3.2 | 1.3–7.6 | Worse in N+ |
| Tumor grade (G1, G2, G3, G4 versus mixed) | 0.01 | 0.23 | 0.7 | 0.4–1.3 | Worse in anaplastic type |
| Ming (infiltrating versus expanding type) | 0.002 | 0.02 | 2.5 | 1.2–5.5 | Worse in infiltrating type |
Six covariates (age, tumor size, depth of invasion, nodal status, Ming histotype, and tumor location) were tested in the multivariate survival analysis using the Cox regression model. KM, Kaplan-Meier.