Table 3.

Summary of Polymorphisms Detected by DHPLC

Gene	Exon	Nucleotide	Change	Codon	Name	DNA no.	In database*
MLH1	4	5′ Intron	C>A		IVS3−29 C>A	7	Yes
	5	5′ Intron	A>G		IVS5+28 A>G	7	No
	6	474	C>T	158	N158N	18	No
	7 and 8	655	A>G	219	I219V	6	Yes
	13	3′ Intron	G>A		IVS13+14 G>A	2, 4	Yes
	13	5′ Intron	C>T		IVS12−54 C>T	7	No
	15	5′ Intron	A>G		IVS14−19 A>G	21	No
	19	2152	C>T	718	H718Y	20, 21, 18	Yes
MSH2	2	5′ Intron	C>G		IVS2−8C>G	634	No
	6	965	G>A	322	G322D	19	Yes
	7	5′ Intron	T>C		IVS7−10 T>C	21	Yes
	10	3′ Intron	G>A		IVS10+12 G>A	21	Yes
	10	5′ Intron	A>T		IVS10−9 A>T	21	Yes
	13	5′ Intron	T>C		IVS13−6 T>C	6, 19, 21	Yes
MSH6	1	116	G>A	39	G39E	0222	Yes
	1	186	C>A	62	R62R	0222	Yes
	2	276	A>G	92	P92P	634	Yes
	3	540	T>C	180	N180N	634	Yes
	5	3′ Intron	T>A		IVS5+14 T>A	007	Yes
	6	3513	T>C	1171	N1171N	005	No
	7	5′ Intron	PolyT variable		IVS6−9polyT	0222	No

^*Database: InSIGHT (www.insight-group.org).