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θ as a function of gap-junctional coupling. Comparison of the noncleft model with 100% junctional INa, the model with 35-nm clefts and 100% junctional INa, and the model with 10-nm clefts and 50% junctional INa. Conduction was supported at lower degrees of coupling when the cleft model was used. For 100% junctional INa and 35-nm clefts, conduction plateaus at ≈15 cm/s as coupling is reduced below 1% and is sustained even in the absence of coupling.
