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. 2006;26:69–76.

TABLE 1. Recurrence rates reported after curettage of giant cell tumors of bone.

Author Year Tumor Characteristics Adjuvant Treatments Number of Patients Recurrence Rate
Capanna et al.3 1990   none 280 45%
Shih et al.33 1998   none* 22 0%
Richardson et al.32 1998   none 16 0%
Blackley et al.29 1999   none 59 12%
Durr et al.10 1999   none 7 43%
Saglik et al.41 1999   none 21 33%
Trieb et al.16 2001   none 14 21%
Turcotte et al.40 2002   none ~50 17%
Khan et al.30 2004 distal radius only none 23 17%
Prosser et al.31 2005 stage 1 &2 none 61 7%
    stage 3 none 52 29%
    recurrent none 29 34%
           
Capanna et al.3 1990   PMMA 187 19%
O'Donnell et al.12 1994   PMMA 49 24%
Bini et al.23 1995   PMMA 38 8%
Saglik et al.41 1999   PMMA 6 0%
Wada et al.42 2002   PMMA 15 7%
Turcotte et al.40 2002   PMMA 62 19%
           
McDonald et al.5 1986   phenol 80 34%
Capanna et al.3 1990   phenol 147 19%
Durr et al.10 1999   phenol 11 9%
Trieb et al.16 2001   phenol 12 25%
Turcotte et al.40 2002   phenol 37 19%
Su et al.15 2004   phenol 56 18%
           
Capanna et al.3 1990   cryotherapy 20 19%
Sheth et al.19 1995 distal radius only cryotherapy 12 25%
Malawer et al.17 1999 primary cryotherapy 86 2.3%
    recurrent cryotherapy 16 37.5%
Turcotte et al.40 2002   cryotherapy 10 0%
           
Zhen et al.21 2004   Zinc Chloride 92 13%
           
Capanna et al.3 1990   phenol+PMMA 33 3%
Ghert et al.43 2002   phenol+PMMA 47 13%
Lackman et al.11 2005 stage 2 & 3 only phenol+PMMA 63 6%
O'Donnell et al.12 1994   phenol+PMMA 11 27%
Saiz et al. 14 2004   phenol+PMMA 40 13%
           
Ward and Li20 2002   H2O2+phenol+
electrocautery+
PMMA (in half)
24 8%

PMMA = polymethylmethacrylate cement.

*

"none" may include the use of a high speed burr, which some authors consider an adjuvant.