TABLE 1. Recurrence rates reported after curettage of giant cell tumors of bone.
Author | Year | Tumor Characteristics | Adjuvant Treatments | Number of Patients | Recurrence Rate |
---|---|---|---|---|---|
Capanna et al.3 | 1990 | none | 280 | 45% | |
Shih et al.33 | 1998 | none* | 22 | 0% | |
Richardson et al.32 | 1998 | none | 16 | 0% | |
Blackley et al.29 | 1999 | none | 59 | 12% | |
Durr et al.10 | 1999 | none | 7 | 43% | |
Saglik et al.41 | 1999 | none | 21 | 33% | |
Trieb et al.16 | 2001 | none | 14 | 21% | |
Turcotte et al.40 | 2002 | none | ~50 | 17% | |
Khan et al.30 | 2004 | distal radius only | none | 23 | 17% |
Prosser et al.31 | 2005 | stage 1 &2 | none | 61 | 7% |
stage 3 | none | 52 | 29% | ||
recurrent | none | 29 | 34% | ||
Capanna et al.3 | 1990 | PMMA | 187 | 19% | |
O'Donnell et al.12 | 1994 | PMMA | 49 | 24% | |
Bini et al.23 | 1995 | PMMA | 38 | 8% | |
Saglik et al.41 | 1999 | PMMA | 6 | 0% | |
Wada et al.42 | 2002 | PMMA | 15 | 7% | |
Turcotte et al.40 | 2002 | PMMA | 62 | 19% | |
McDonald et al.5 | 1986 | phenol | 80 | 34% | |
Capanna et al.3 | 1990 | phenol | 147 | 19% | |
Durr et al.10 | 1999 | phenol | 11 | 9% | |
Trieb et al.16 | 2001 | phenol | 12 | 25% | |
Turcotte et al.40 | 2002 | phenol | 37 | 19% | |
Su et al.15 | 2004 | phenol | 56 | 18% | |
Capanna et al.3 | 1990 | cryotherapy | 20 | 19% | |
Sheth et al.19 | 1995 | distal radius only | cryotherapy | 12 | 25% |
Malawer et al.17 | 1999 | primary | cryotherapy | 86 | 2.3% |
recurrent | cryotherapy | 16 | 37.5% | ||
Turcotte et al.40 | 2002 | cryotherapy | 10 | 0% | |
Zhen et al.21 | 2004 | Zinc Chloride | 92 | 13% | |
Capanna et al.3 | 1990 | phenol+PMMA | 33 | 3% | |
Ghert et al.43 | 2002 | phenol+PMMA | 47 | 13% | |
Lackman et al.11 | 2005 | stage 2 & 3 only | phenol+PMMA | 63 | 6% |
O'Donnell et al.12 | 1994 | phenol+PMMA | 11 | 27% | |
Saiz et al. 14 | 2004 | phenol+PMMA | 40 | 13% | |
Ward and Li20 | 2002 | H2O2+phenol+ electrocautery+ PMMA (in half) |
24 | 8% |
PMMA = polymethylmethacrylate cement.
"none" may include the use of a high speed burr, which some authors consider an adjuvant.