Figure 6.

GAP43 mRNA is an SMD target. (A) RT–PCR demonstrating that depleting cells of Stau1 or Upf1 increases the cellular abundance of GAP43 mRNA. RNA derived from samples used in Figure 3. (B) As in Figure 4, except that FLuc-GAP43 3′-UTR and FLuc-ARF1 SBS mRNAs were analyzed. (C) As in Figure 5, except that fos-FLuc-GAP43 3′-UTR mRNA was analyzed. Results are representative of two independently performed experiments.