Table 6.
Gene Ontology of the sequences with significant Blastx hits in UniProt
| GO Categories | Normal | Infected | P value |
| Biological process | |||
| protein modification | 44 (0.66%) | 49 (0.67%) | 1.00 |
| nucleic acid metabolism | 0 (0.00%) | 0 (0.00%) | 1.00 |
| electron transport | 1236 (18.53%) | 1348 (18.47%) | 0.93 |
| cell adhesion | 12 (0.18%) | 9 (0.12%) | 0.51 |
| nucleosome assembly | 6 (0.09%) | 10 (0.14%) | 0.46 |
| lipid metabolism | 13 (0.19%) | 21 (0.29%) | 0.30 |
| protein metabolism** | 506 (7.59%) | 490 (6.71%) | 0.05 |
| transport** | 1125 (16.86%) | 1133 (15.52%) | 0.03 |
| phosphate metabolism** | 247 (3.70%) | 219 (3.00%) | 0.02 |
| microtubule-based movement** | 3 (0.04%) | 16 (0.22%) | 0.01 |
| response to external stimulus** | 39 (0.58%) | 14 (0.19%) | 0.00 |
| signal transduction** | 72 (1.08%) | 30 (0.41%) | 0.00 |
| carbohydrate metabolism ** | 94 (1.41%) | 232 (3.18%) | 0.00 |
| Cellular component | |||
| mitochondrion | 1347 (20.19%) | 1434 (19.65%) | 0.43 |
| ribosome | 258 (3.87%) | 299 (4.10%) | 0.52 |
| cytoskeleton** | 193 (2.89%) | 132 (1.81%) | 0.00 |
| nucleus | 73 (1.09%) | 93 (1.27%) | 0.35 |
| membrane | 1273 (19.08%) | 1384 (18.96%) | 0.86 |
| extracellular matrix | 3 (0.04%) | 1 (0.01%) | 0.35 |
| extracellular region | 39 (0.58%) | 62 (0.85%) | 0.07 |
| unlocaliyed protein complex | 2 (0.03%) | 3 (0.04%) | 1.00 |
| Molecular component | |||
| peroxidase activity | 9 (0.13%) | 4 (0.05%) | 0.17 |
| carbohydrate binding** | 41 (0.61%) | 75 (1.03%) | 0.01 |
| metal ion binding** | 625 (9.37%) | 490 (6.71%) | 0.00 |
| nucleic acid binding | 157 (2.35%) | 157 (2.15%) | 0.42 |
| nucleotide binding | 133 (1.99%) | 139 (1.90%) | 0.71 |
| protein binding** | 97 (1.45%) | 77 (1.06%) | 0.04 |
| catalytic activity | 1716 (25.72%) | 1886 (25.84%) | 0.88 |
| enyyme regulator activity | 14 (0.21%) | 12 (0.16%) | 0.56 |
| motor activity** | 127 (1.90%) | 79 (1.08%) | 0.00 |
| obsolete molecular function | 0 (0.00%) | 0 (0.00%) | 1.00 |
| antimicrobial peptide activity | 0 (0.00%) | 0 (0.00%) | 1.00 |
| signal transducer activity** | 43 (0.64%) | 21 (0.29%) | 0.00 |
| structural molecule activity** | 367 (5.50%) | 860 (11.78%) | 0.00 |
| transporter activity** | 1405 (21.06%) | 1358 (18.61%) | 0.00 |
| translation regulator activity | 56 (0.84%) | 45 (0.62%) | 0.13 |
** indicates statistically significant GO term with P < 0.05 evaluated by Fisher's exact test