Table 2.
Frequency, age distribution and pattern of infiltration in the different lymphoma entities presenting in the liver (Berlin/Cologne 1994–2003)
| Berlin | Cologne | Berlin + Cologne, n (%) | Age (range) | Age (mean) | Male/female | Pattern | Density of infiltrate | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sinusoidal | Portal | Nodular | Dense | Loose | |||||||
| Diffuse large B-cell lymphoma (DLBCL)a | 52 | 28 | 80(39) | 16–87 | 64 | 50/30 | 6 | 19 | 72 | 75 | 5 |
| T-cell rich B-cell lymphoma (TCRBCL) | 9 | 4 | 13(6) | 35–85 | 59 | 9/4 | 0 | 11 | 5 | 0 | 13 |
| B-cell chronic lymphocytic leukemia (B-CLL) | 13 | 13 | 26(13) | 44–82 | 66 | 16/10 | 7 | 25 | 2 | 25 | 1 |
| Classical Hodgkin lymphoma (cHL) | 10 | 13 | 23(11) | 21–91 | 54 | 14/9 | 1 | 21 | 10 | 3 | 20 |
| Follicular lymphoma (FL) | 11 | 3 | 14(7) | 38–83 | 62 | 7/7 | 0 | 11 | 4 | 14 | 0 |
| Marginal zone lymphoma (MZL) | 6 | 1 | 7(3) | 49–80 | 70 | 6/1 | 2 | 7 | 0 | 6 | 1 |
| Leukemic Plasmacytoma (PL) | 4 | 2 | 6(3) | 61–88 | 70 | 4/2 | 4 | 1 | 2 | 5 | 1 |
| Burkitt lymphoma (BL) | 5 | – | 5(2) | 30–70 | 47 | 3/2 | 0 | 0 | 5 | 5 | 0 |
| Mantle cell lymphoma (MCL) | 3 | – | 3(1) | 60–66 | 63 | 2/1 | 1 | 3 | 1 | 3 | 0 |
| B-lymphoblastic leukaemia (B-ALL) | 2 | – | 2(1) | 18–28 | 22 | 1/1 | 2 | 0 | 0 | 2 | 0 |
| Hairy cell leukaemia (HCL) | 1 | – | 1 | 42 | – | 0/1 | 1 | 0 | 0 | 1 | 0 |
| Peripheral T-cell lymphoma, unspecified (pTCL) | 13 | 5 | 18(9) | 38–84 | 62 | 14/4 | 6 | 6 | 8 | 11 | 7 |
| Anaplastic large cell lymphoma (ALCL)b | 5 | – | 5(2) | 24–76 | 58 | 5/0 | 3 | 3 | 2 | 2 | 3 |
| Hepatosplenic T-cell lymphoma (HSTCL) | 1 | 1 | 2(1) | 38–51 | 45 | 2/0 | 2 | 0 | 0 | 2 | 0 |
| Total | 135 | 70 | 205 | ||||||||
aIncluding centroblastic (n = 69), immunoblastic (n = 3) and anaplastic variant (n = 8)
bIncluding one anaplastic large cell lymphoma kinase (ALK) protein positive case