Table 6.
Quarter-site coupling mode change for human and mouse p53RE with various spacers
Number of spacer | Q1234 | T13 | T24 | H14 | H23 | Correlation (R2) | |
---|---|---|---|---|---|---|---|
0 | Human | 14.99 | 17.18 | 19.67 | 36.99 | 11.17 | 0.8871 |
Mouse | 17.88 | 18.28 | 22.40 | 26.37 | 15.06 | ||
1 | H | 18.68 | 18.32 | 22.77 | 19.93 | 20.30 | 0.000 |
M | 20.91 | 20.84 | 20.67 | 16.9 | 20.68 | ||
2 | H | 18.54 | 18.58 | 21.77 | 20.35 | 20.75 | 0.5725 |
M | 18.39 | 19.93 | 22.20 | 20.03 | 19.45 | ||
3 | H | 29.80 | 18.08 | 20.15 | 17.60 | 14.36 | 0.0696 (0.3968)a |
M | 20.02 | 20.71 | 20.23 | 19.66 | 19.38 | ||
4 | H | 17.94 | 19.77 | 22.52 | 20.92 | 18.86 | 0.3468 |
M | 13.90 | 27.77 | 28.40 | 14.10 | 15.84 | ||
5 | H | 18.8 | 19.58 | 22.23 | 19.68 | 19.71 | 0.7523 |
M | 18.26 | 19.87 | 21.72 | 19.39 | 20.76 | ||
6 | H | 17.96 | 18.47 | 23.49 | 20.04 | 20.03 | 0.0142 |
M | 19.94 | 21.40 | 20.95 | 19.13 | 18.60 | ||
7 | H | 19.28 | 18.83 | 21.30 | 18.23 | 22.36 | 0.0017 |
M | 19.03 | 20.67 | 20.75 | 20.01 | 19.54 | ||
8 | H | 18.14 | 18.93 | 22.50 | 20.42 | 20.02 | 0.0031 (0.3968)a |
M | 24.37 | 15.39 | 20.20 | 15.86 | 21.07 | ||
9 | H | 19.57 | 18.77 | 21.33 | 20.61 | 19.72 | 0.6537 |
M | 19.02 | 19.42 | 21.51 | 19.90 | 20.15 | ||
10 | H | 18.12 | 19.96 | 22.63 | 19.35 | 20.95 | 0.5816 |
M | 18.76 | 18.79 | 24.18 | 19.90 | 18.75 | ||
11 | H | 18.47 | 20.30 | 21.72 | 19.21 | 20.31 | 0.2669 |
M | 19.30 | 17.84 | 22.59 | 20.46 | 19.78 | ||
12 | H | 18.61 | 19.06 | 21.85 | 19.78 | 20.70 | 0.7691 |
M | 19.10 | 18.06 | 22.7 | 18.13 | 21.20 | ||
13 | H | 18.78 | 18.91 | 21.45 | 20.24 | 20.62 | 0.4743 |
M | 18.43 | 20.35 | 21.95 | 19.60 | 19.67 | ||
14 | H | 18.23 | 16.95 | 21.90 | 24.85 | 18.06 | 0.735 |
M | 18.80 | 18.80 | 22.22 | 21.31 | 18.89 |
a The correlation coefficient of human p53REs with 3 bp spacer and mouse p53REs with 8 bp spacer is R2 = 0.3968