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. 2007 Apr 16;35(9):3016–3031. doi: 10.1093/nar/gkm197

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© 2007 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Models of L20 binding to its operator. (A) L20 binding to H2/L1 hybrid site produced by interaction between a region of site 2 (H2) and a region of site 1 (L1). In this model, the remaining regions of both sites are unable to form a L20-binding site. (B) L20 binding to one preformed site excludes binding to the second site either by structural change of the latter or by steric hindrance. (C) L20 binding to site 2 induces a structural change of site 1 rendering the latter competent for L20 binding and/or local increase of L20 concentration which increases the L20-binding efficiency of site 1.