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Summary of Biochemical activities of HpDnaBWt and di.erent mutant variants as shown in Figures 2 and 3
| Protein | ATP-binding | ATPase | ATPase DNA-stimulated | Helicase |
|---|---|---|---|---|
| HpDnaBWt | +++ | +++ | +++ | +++ |
| HpDnaBMut | − | − | − | − |
| DelN1 | ND | ++ | ++ | +++ |
| DelN2 | ++ | ++ | ++ | ++ |
| DelN3 | ++ | + | + | − |
| DelN4 | − | − | − | − |
| DelC1 | − | − | − | − |
| Del34 | ND | − | ND | − |
‘+++’, ‘++’ and ‘+’ signs stand for maximum, moderate and lowcatalytic activity, respectively, whereas ‘−’ stands for no activity. ‘ND’ stands for experiment not done
