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Polyacrylamide gel of oligonucleotides following incubation with HeLa cell nuclear extract. The sequence of the duplex is indicated in Fig. 1. The identity of the base pair at the cleavage site is indicated in the figure. Lanes marked HmU-control and HmU ss refer to the HmU-containing single strand not treated with extract, and the HmU-containing single strand treated with extract.
