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Excision activity of cloned UDG and TDG (μmol oligo/μg protein/min)
| Substrate | UDG | TDG |
|---|---|---|
| U ss | 4.3 × 10−6 | <1 × 10−12 |
| U:A | 7.8 × 10−6 | <1 × 10−12 |
| U:G | 1.0 × 10−5 | 2.3 × 10−6 |
| HmU ss | <1 × 10−12 | <1 × 10−12 |
| HmU:A | <1 × 10−12 | <1 × 10−12 |
| HmU:G | <1 × 10−12 | 9.0 × 10−8 |
| T:G | <1 × 10−12 | 1.5 × 10−7 |
Excision activities of cloned UDG and TDG on oligonucleotide substrates containing U, HmU, or T [single-stranded (ss), paired with A, or mispaired with G].
