Depletion of hTFIIIB50 from a partially purified fraction (cEDF 0.2)
using antibodies against either hTFIIIB90 or hTFIIIB50.
(A) Ten microliters of cEDF 0.2 (lane 1), preimmune
control antibody flow-through (FT, lane 2), anti-hTFIIIB90 antibody
flow-through (lane 3), or anti-hTFIIIB90 eluate (lane 4) was separated
by SDS/12.5% PAGE and transferred onto nitrocellulose. A 1:10,000
dilution of anti-hTFIIIB50 antibody in PBS-0.05% Tween 20 and 5% skim
milk powder was used for Western blot analyses that were performed as
described (8). (B) Ten microliters of cEDF 0.2 (lane 1),
anti-hTFIIIB50 antibody flow-through from cEDF 0.2 (lane 2) or
anti-hTFIIIB50 eluate from cEDF 0.2 (lane 3) was separated by
SDS/12.5% PAGE and transferred onto nitrocellulose. SDS/PAGE and
Western blot procedures were described (A; ref. 8).