Table 2.
Body Weight And Liver Size In Rats Exposed To Diets Of Differing Composition in utero.
Maternal diet group |
|||||||
---|---|---|---|---|---|---|---|
Control |
LPA |
LPE |
LPM |
LPL |
|||
Sex | Age | ||||||
Body wt | M | 1 | 87.4±7.9 | 82.9±4.3 | 72.9±5.8 | 87.1±7.2 | 73.8±4.6 |
(g) | 9 | 676.9±45.0 | 692.3±54.4 | 664.6±23.1 | 724.6±38.5 | 661.8±46.9 | |
18 | 821.7±67.8 | 764.9±16.5 | 749.0±46.7 | 637.0±60.9 | 762.4±44.2 | ||
F | 1 | 77.8±3.3 | 69.4±5.4 | 73.2±6.3 | 80.6±6.9 | 75.2±4.0 | |
9 | 339.9±14.0 | 380.8±32.0 | 451.1±55.8 | 394.2±17.1 | 411.2±40.9 | ||
18 | 419.9±20.4 | 460.9±21.7 | 507.3±47.4 | 413.3±40.0 | 493.1±26.1 | ||
Liver | M | 1 | 4.64±0.47 | 4.10±0.33 | 3.52±0.41 | 4.56±0.32 | 3.50±0.29 |
(g) | 9 | 27.10±1.20 | 27.54±2.64 | 26.30±1.64 | 30.01±2.38 | 25.99±1.62 | |
18 | 31.33±1.31 | 28.64±1.55 | 28.51±2.01 | 28.97±3.52 | 31.75±0.69 | ||
F | 1 | 3.98±0.25 | 3.49±0.37 | 3.62±0.42 | 3.99±0.42 | 3.82±0.31 | |
9 | 13.16±0.61 | 14.64±1.39 | 17.48±2.53 | 15.50±0.78 | 13.10±0.47 | ||
18 | 18.01±1.54 | 16.94±1.33 | 19.98±2.39 | 17.70±1.96 | 16.49±1.16 | ||
Liver | |||||||
(% body wt) | M | 1 | 5.28±0.26 | 5.36±0.23 | 5.01±0.24 | 5.30±0.21 | 4.71±0.17 |
9 | 4.16±0.36 | 3.96±0.13 | 3.94±0.15 | 4.11±0.1 | 23.72±0.17 | ||
18 | 3.91±0.24 | 3.73±0.15 | 3.89±0.42 | 4.54±0.50 | 4.24±0.24 | ||
F | 1 | 5.20±0.19 | 4.94±0.15 | 4.89±0.21 | 4.93±0.23 | 5.05±0.20 | |
9 | 3.90±0.15 | 3.84±0.11 | 3.82±0.14 | 3.93±0.08 | 3.61±0.14 | ||
18 | 4.38±0.49 | 3.67±0.21 | 3.95±0.28 | 4.71±0.87 | 3.35±0.18 |
All data are shown as mean ± SEM for 5-10 observations per group. ANOVA indicated that body weight was influenced by sex (P<0.001), age (P<0.001) and the interaction of age and sex (P<0.001). Liver weight was influenced by age (P<0.001), sex (P<0.001) and the age x sex interaction (P<0.001). Liver weight as a percentage of body weight was influenced by sex (P=0.034), age (P<0.001).