. 2006 Aug 24;576(Pt 3):887–901. doi: 10.1113/jphysiol.2006.113951

Table 1.

Spatio-temporal properties of Ca²⁺ sparks in intact and permeabilized cerebral artery myocytes under different conditions

Treatment	Frequency (events s⁻¹ μm⁻¹)	Amplitude (F/F₀)	Duration (ms)	Width (μm)
Intact (151)	0.010 ± 0.001	1.75 ± 0.04	55.5 ± 2.6	2.6 ± 0.1
Permeabilized
Low [EGTA] (61)	0.024 ± 0.004^*	1.47 ± 0.02^*	84.0 ± 7.6 ^*	2.9 ± 0.2
Low [EGTA]+ sorcin (36)	0.020 ± 0.006^*	1.32 ± 0.02^*^†	45.1 ± 4.4^*^†	2.3 ± 0.2^†
Low [EGTA]+ F112L-sorcin (144)	0.025 ± 0.003^*^†	1.49 ± 0.01^*^†	58.2 ± 3.2^*^†	2.94 ± 0.1^†
Permeabilized
High [EGTA] (123)	0.019 ± 0.003^*	1.71 ± 0.04	42.3 ± 2.2^*	2.2 ± 0.08 ^*
High [EGTA]+ sorcin (62)	0.017 ± 0.004^*	1.46 ± 0.03^*^†	34.7 ± 2.0 ^*^†	1.95 ± 0.11 ^*^†

Data presented as mean ± s.e.m. of measurements. Number of Ca²⁺ sparks recorded is indicated in parenthesis.

Significant difference (P < 0.05) with intact Ca²⁺ spark parameters.

^†

Significant difference (P < 0.05) with parameters in the row above, for example, the frequency of Ca²⁺ sparks in cells perfused with F112L-sorcin was significantly higher than that in cells perfused with WT-sorcin. Duration and width were measured at half-maximal amplitude.