Table 3.
Single channel permeabilities (×10−10 mm3 min−1) for Alexa dyes through connexin channels
Cx | Alexa 350 | Alexa 488 | Alexa 594 |
---|---|---|---|
45.6 | 3.24 ± 0.24 (7) | 0.94 ± 0.12 (6) | 0 (6) |
43 | 1.14 ± 0.08 (5)* | 2.93 ± 0.02 (4)*† | 1.23 ± 0.06 (6)* |
45.6–43 N | 1.6 ± 0.08 (6)* | 1. 6 ± 0.05 (5)* | 0.91 ± 0.07 (4)* |
Values are mean ±s.e.m. of (AP)pore (units of 10−10 mm3 min−1). Number of data sets used in calculating permeability shown in parentheses. The (AP)pore of Cx43 and Cx45.6–43N were significantly different from Cx45.6 when evaluated with a student's t test
P < 0.001. The (AP)pore of Cx43 was significantly different from Cx45.643N when evaluated with a student's t test
P < 0.001.