Table 3.

Ventilatory responses to hyperoxic hypercapnia in WT and HET mice before and after CIH

	Before CIH		After CIH
	100% O2	5% CO2	100% O2	5% CO2
WT (n = 8)
RR (breaths min−1)	167 ± 7	254 ± 9	153 ± 6	265 ± 14
VT (μl g−1)	1.64 ± 0.15	2.09 ± 0.19	1.82 ± 0.17	2.57 ± 0.23
V˙E (ml g−1 min−1)	0.27 ± 0.02	0.52 ± 0.03	0.28 ± 0.02	0.67 ± 0.05*
HET (n = 8)
RR (breaths min−1)	156 ± 7	238 ± 15	156 ± 12	274 ± 10*
VT (μl g−1)	1.86 ± 0.13	2.6 ± 0.2	1.93 ± 0.13	2.93 ± 0.27
V˙E (ml g−1 min−1)	0.28 ± 0.01	0.61 ± 0.05	0.30 ± 0.03	0.81 ± 0.09*

Data presented are mean +s.e.m.

^*P < 0.05 compared with the responses before CIH.