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Fibroblast growth factor (FGF)-10 antagonizes retinoid signalling E11.5d dorsal pancreatic buds were isolated from FGF receptor 2IIIb isoform homozygote knock-out embryos (A–D), cultured for 2 days and then cultured for a further 3 days without treatment (A), or with: 10 μg/ml FGF-10 (B), 1 μM retinoic acid (RA) (C), or 10 μg/ml FGF-10+1 μM RA (D). Buds were fixed and stained for (A–D) amylase (green)/insulin (red).
