Table 1.
Sequence changes observed for pnuH* mutant alleles.
| Nucleotide sequence | ||||
|---|---|---|---|---|
| Strain | Genotype | Wild type | Mutanta | Amino acid change |
| TT16290 | pnuH183 | CTG | CAG | Leu866Gln |
| TT16294 | pnuH187 | CGT | CCT | Arg792Pro |
| TT16296 | pnuH189 | TGG | CGG | Trp909Arg |
| TT16297 | pnuH190 | CGT | CCT | Arg792Pro |
| TT16299 | pnuH192 | GGC | AGC | Gly924Ser |
| TT18216 | pnuH255 | GCG | CCG | Ala918Pro |
The underlined base indicates the change in the DNA sequence.
DNA sequence and consequent amino acid changes associated with the pnu mutations at the mscK locus that confer the ability to grow in the presence of low concentrations of quinolinic acid.