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. 2007 Jun 21;117(7):1763–1770. doi: 10.1172/JCI30178

Figure 2. RGC degeneration in glutamate transporter mutant mice.

Figure 2

(A) H&E staining of retinal sections during postnatal development. WT, GLAST+/–, and GLAST–/– mice are littermates. EAAC1+/– and EAAC1–/– mice are littermates. (B) Quantification of RGC number in glutamate transporter mutant mice. The number of neurons in the GCL was counted in the retinal section from one ora serrata through the optic nerve to the other ora serrata at 0, 1, 2, 3, 5, 8, 16, and 32 weeks of age. Each plot represents the results of 3 to 6 independent experiments. Scale bar: 50 μm (A). NBL, neuroblast layer.