Table 1.

Effects of DNA binding on pressure-induced dissociation of E2c

DNA (18-mer)	ΔV, ml/mol	ΔGd, kcal/mol	Kd	ΔΔGd, kcal/mol
None	87.9  ± 10.2*	10.6  ± 0.4*	17.6 nM  ± 0.6*	—
	91.3  ± 3.6†	10.6  ± 0.1†	17.6 nM  ± 0.2†
Poly(A-T)	85.9  ± 11.7	15.1  ± 0.5	9.2 pM  ± 0.315	4.5
E2-DBS	84.8  ± 7.9	17.3  ± 0.3	0.22 pM  ± 0.00413	6.7

^*From fit of Fig. 1. 

^† From fit of Fig. 5.