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. 2007 May 16;7:39. doi: 10.1186/1471-2180-7-39

Table 2.

SNPs in the alkA region

	*Downstream region*			← *ada/alkA*^b					*Upstream region*

SNP position^a	SNP1 1471.218	SNP2 1471.659	SNP3 1477.028	Codon 337 1478.108	Codon 269 1478.312	Codon 79 1478.883	Codon 12 1479.085	Codon 11 1479.088	SNPs 4, 5, 6 1480.972, 1482.627, 1484.708
Strains	In CAR strains

M.tb alkA 79+337^c	wt	C→T	wt	ACT→AAT	wt	TGG→TAG	wt	wt	T→C, T→C, A→C
M.tb alkA 337^d	wt	C→T	wt	ACT→AAT	wt	wt	wt	wt	T→C, T→C, A→C
M.bv CAR^e	C→T	C→T	wt	wt	wt	wt	ATC→GTC	wt	T→C, T→C, A→C
	in other strains

M.bv AF2122	C→T	C→T	C→-	wt	CTG→CTA	TGG→TAG	ATC→GTC	wt	T→C, T→C, A→C
M. bv BCG	C→T	C→T	wt	wt	CTG→CTA	wt	ATC→GTC	wt	T→C, T→C, A→C
M.tb 210	wt	C→T	wt	wt	wt	wt	ATC→GTC	GCG→ACG	T→C, T→C, A→C
M.tb CDC1551	wt	C→T	wt	wt	wt	wt	wt	wt	T→C, T→C, A→C
M.tb H37Rv	wt	wt	wt	wt	wt	wt	wt	wt	wt

^aSNP position = base position according to the numbering of the H37Rv genome [18]

^bada/alkA coding sequence is on the minus strand

^cisolates from CAR that harbour variations at codon 79 and 337 in ada/alkA, 8/8 isolates sequenced

^disolates from CAR that harbour variations at codon 337 in ada/alkA, 5/25 isolates sequenced

^eM. bovis isolate from CAR sequenced (one isolate)

CAR, Central African Republic ; M.bv, Mycobacterium bovis ; M.tb, Mycobacterium tuberculosis ; wt, wild type (H37Rv).