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. 2007 Jun 13;104(26):10818–10823. doi: 10.1073/pnas.0704525104

Fig. 1.

Fig. 1.

The overall complex structure of c-JMJD2A with the H3K36me3 peptide in the presence of NOG (orange), Fe(II) (pink), and Zn (purple). (A) c-JMJD2A is shown as a ribbon model with the Jumonji N domain (green), the long β hairpin (purple), the mixed structural motif (gray), the Jumonji C domain (light blue), the C-terminal domain (pink), and the methylated H3K36 peptide (yellow). Seventeen of the 22 residues (residues 27–43 from histone 3) of the methylated peptide are ordered in the structure (molecule A). (B) A stick and ball model of the peptide on the surface of c-JMJD2A colored according to the electrostatic potential of the residues (red and blue represent negatively and positively charged areas, respectively). All structural figures were made by using the PyMOL program (http://pymol.sourceforge.net).