Table 3.

Excess Cdkn1c does not affect sexual maturity.

	Age at 1st plug (days)		Age at 1st litter (days)
	WT males	5D3 male	WT female	5D3 female
	43	39	54	58
	38	37	56	69
	39	38	58	57
	37	38	56	55
	46		56	56
	37		55	57
Average (s.d.)	40 (3.69)	38 (0.82)	56 (1.33)	59 (5.16)

There was no significance difference in time to first plug between transgenic males and wild type littermates (P = 0.33). Transgenic females had their litters slightly later than wild type females. Although this difference did not show up as significant (P = 0.22), there was a large variation in timing within the transgenic females from 56 to 69 days. Furthermore, two females in this study never became pregnant.