Table 2.
Leukocyte aggregation-inducing effects of lipid fractions of Plasmodium vivax paroxysm plasma and of P. vivax schizont extracts with or without supplementation with recombinant human cytokines (TNFα, GM-CSF, IL-6 and IL-10).
| Expt. No. | Sample | % R CAI (Median) | 25% | 75% |
| 1 | P1 | 26.30 | 20.10 | 30.60 |
| 2 | P2 | 4.50 | 3.40 | 8.60 |
| 3 | P3 | 4.20 | 3.50 | 6.40 |
| 4 | P4 | 8.50 | 6.80 | 11.80 |
| 5 | P5 | 1.00 | 0.20 | 1.30 |
| 6 | P1 + Cytokines | 38.20 | 34.20 | 46.50 |
| 7 | P2 + Cytokines | 8.70 | 5.60 | 10.90 |
| 8 | P3 + Cytokines | 8.60 | 4.60 | 12.40 |
| 9 | P4 + Cytokines | 24.60 | 22.50 | 31.70 |
| 10 | P5 + Cytokines | 1.20 | 0.50 | 3.60 |
| 11 | S1 | 3.1 | 1.4 | 6.4 |
| 12 | S2 | 2.5 | 1.3 | 5.9 |
| 13 | S3 | 2.9 | 1.2 | 7.4 |
| 14 | S4 | 14.3 | 12.3 | 18.6 |
| 15 | S5 | 1 | 0.2 | 2.4 |
| 16 | S1 + Cytokines | 10.4 | 7.6 | 13.9 |
| 17 | S2 + Cytokines | 3.8 | 2.5 | 6.4 |
| 18 | S3 + Cytokines | 2.7 | 1.9 | 6.5 |
| 19 | S4 + Cytokines | 26.2 | 21.9 | 30.4 |
| 20 | S5 + Cytokines | 1.1 | 0.3 | 2.1 |
% RCAI: % Relative Cell Aggregation Index (median)
25%–75%: 25th and 75th percentiles
Different fractions of P. vivax schizont extracts (S1 – acetone fraction, S2 – ethanol fraction, S3 – petroleum ether fraction, S4 – diethyl ether fraction and S5 – remaining fraction ) and similar fractions of paroxysm plasma ( P1 – acetone fraction, P2 – ethanol fraction, P3 – petroleum ether fraction, P4 – diethyl ether fraction and P5 – remaining fraction ) were tested for their ability to induce cell aggregation with or without supplementation with recombinant human cytokines (TNFα, GM-CSF, IL-6 and IL-10).
The table provides the median values together with the interquartile range (25%–75%).