Skip to main content
. 2007 Mar 26;51(6):2053–2064. doi: 10.1128/AAC.00873-06

FIG. 6.

FIG. 6.

Synergistic and antagonistic volumes (sum percentage of the interactions presented in Fig. 5) of the double combinations voriconazole-caspofungin (A), amphotericin B-caspofungin (B), and amphotericin B-voriconazole (C) with increasing concentrations of amphotericin B (AMB), voriconazole (VOR), and caspofungin (CAS), respectively. With increasing amphotericin B and voriconazole concentrations, respectively, the synergistic volumes of the voriconazole-caspofungin and amphotericin B-caspofungin double combinations decrease and the antagonistic volumes increase. With increasing caspofungin concentrations, the synergistic volumes of the amphotericin B-voriconazole double combination increase and the antagonistic volumes decrease. Points and error bars represent mean sum percentages and standard errors, respectively, among the three isolates. The squares and circles on the y axis of each graph represent the sum percentages of synergistic and antagonistic volumes, respectively, of only the double combinations voriconazole-caspofungin (A), amphotericin B-caspofungin (B), and amphotericin B-voriconazole (C) in the absence of the third drug.