TABLE 2.
Apoptotic cell numbers in dentate gyrus of animals with experimental pneumococcal meningitis treated with ceftriaxone compared with those in animals treat with daptomycin
| Time (h) after infection | No. (%) of apoptotic cells in dentate gyrus witha:
|
|
|---|---|---|
| CRO treatment | DAP treatment | |
| 20 | 5.6 ± 3.8 (9) | 5.5 ± 2.4 (9) |
| 24 | 18.4 ± 7.6 (9) | 14.9 ± 11.5 (9) |
| 40 | 9.0 ± 9.6 (28) | 6.1 ± 10.2 (30) |
a
Apoptotic cells were more frequent in the ceftriaxone-treated animals at all time points tested, but the differences between all treatment groups did not reach statistical significance. CRO, ceftriaxone; DAP, daptomycin.