TABLE 1.

Topical microbicide products and placebos tested

Product (reference)	Constituent	Placebo	Placebo constituent
CAP (21)	Pharmaceutical excipient; 13% polyanionic polymer with antimicrobial activity	Hydroxyethyl cellulose	3.25% aqueous gel
PRO 2000 (24)	Naphthalene sulfonate polymer (4%) with antimicrobial activity	Cross-linked polyacrylic acid polymer-based aqueous gel	1% gelling agent with pH buffering capacity
SPL7013 (5)	Lysine dendrimer (5%) in which the surface has been derivatized with sodium naphthalene disulfonate groups with antimicrobial activity	Cross-linked polyacrylic acid polymer-based aqueous gel	5% gelling agent with pH buffering capacity
UC781 (3)	Tight binding (0.1%) nonnucleoside reverse transcriptase inhibitor; anti-HIV-1 activity only	Cross-linked polyacrylic acid polymer-based aqueous gel	1% gelling agent with pH buffering capacity