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Effect of NP siRNA on Lassa virus and LCMV replication as tested in infectious focus reduction assay. Vero cells were transfected with 50 pmol of NP siRNA and infected with 100 to 200 PFU Lassa virus AV or LCMV WE. Nonsense (nons.) siRNA was used as a control. Cells were overlaid with methylcellulose, and the number of infectious foci was visualized after 5 days by immunological staining. The numbers in parentheses are the numbers of foci.
