TABLE 1.
Conserved RNA termini of arenaviruses
| Gene | Sequence of RNA terminusa | Viruses sequenced (GenBank accession no.)b |
|---|---|---|
| GPC | CGCACCGGGGATCCTAGGC | Lassa virus Josiah (M15076), Lassa virus AV (AF246121), LCMV Armstrong (M20869), LCMV WE (M22138), Pichinde virus (K02734), Oliveros virus (U34248), Sabia virus (U41071), Allpahuayo virus (AY012686) |
| NP | CGCACAGTGGATCCTAGGC | Lassa virus Josiah (J04324), Lassa virus AV (AF246121), Lassa virus GA391 (K03362), LCMV Armstrong (J02242, M20869), LCMV WE (M22138), Pichinde virus (J02279, K02734), Oliveros virus (U34248), Tacaribe virus (J02411) |
| Z | CGCACCGGGGATCCTAGGC | Lassa virus Josiah (U73034), LCMV Armstrong (M27693), LCMV WE (AF004519), Tacaribe virus (J04340) |
| L | CGCACCGAGGATCCTAGGC | Lassa virus Josiah (U73034), LCMV Armstrong (J04331), LCMV WE (AF004519), Pichinde virus (J02277) |
a
Sequences are written in 5′-3′ orientation in mRNA sense. Positions with natural variability between the four termini are underlined.
b
The table lists all viruses for which there is published evidence that the authentic termini have been sequenced (for the references see the GenBank entries). Additional terminal sequences, which do not represent authentic virus sequences, are also deposited in GenBank. They are derived from primers used for reverse transcription or PCR amplification of the arenavirus genome and were mistakenly not removed from the sequence entry. Some of the primer-derived sequences do not match the authentic sequence due to the use of consensus primers.