TABLE 1.
Demographic and clinical characteristics of patients evaluated in a comparative study of telithromycin and doxycycline for treatment of scrub typhus
| Parameter | Result for treatment groupa:
|
|
|---|---|---|
| Telithromycin (n = 47) | Doxycycline (n = 45) | |
| Demographic data | ||
| Age (mean yr ± SD) | 60.2 ± 15.9 | 61.6 ± 12.8 |
| Gender (no. of male/no. of female) | 14/33 | 18/27 |
| Duration of illness before admission (mean days ± SD) | 6.38 ± 3.9 | 6.64 ± 3.5 |
| Clinical symptoms and signs (no. [%] of patients) | ||
| Headache | 40 (85.1) | 36 (80) |
| Myalgia | 36 (76.6) | 34 (75.6) |
| Skin rash | 45 (95.7) | 42 (93.3) |
| Eschar | 42 (89.4) | 40 (88.9) |
| Laboratory measurements | ||
| White blood cell count (no. of cells × 1,000/mm3) | 6.7 ± 3.3 | 7.7 ± 3.8 |
| Hemoglobin (g/dl) | 12.5 ± 1.4 | 12.9 ± 1.6 |
| Platelet count (no. of cells × 1,000/mm3) | 141.4 ± 50.5 | 148.7 ± 47.6 |
| AST (IU/liter) | 102.3 ± 82.9 | 84.9 ± 57.7 |
| ALT (IU/liter) | 88.4 ± 94.5 | 71.8 ± 55.9 |
| Serum creatinine (mg/dl) | 1.1 ± 0.3 | 1.1 ± 0.4 |
a
There was no significant difference in baseline characteristics between the two groups (P > 0.05). Values are means ± SD.