TABLE 2.
MICs of β-lactams for selected strainsa
| β-Lactam(s)b | MIC (μg/ml) for:
|
||
|---|---|---|---|
| A. johnsonii 7037 |
E. coli
|
||
| TOP10(p7037-B2) | TOP10 | ||
| Amoxicillin | >512 | >512 | 2 |
| Amoxicillin + CLA | 1 | 32 | 2 |
| Ticarcillin | >512 | >512 | 2 |
| Ticarcillin + CLA | 2 | 128 | 2 |
| Piperacillin | 64 | 128 | 1 |
| Piperacillin + TZB | 2 | 1 | 1 |
| Cephalothin | >512 | 8 | 2 |
| Cefuroxime | >512 | 4 | 2 |
| Ceftazidime | >512 | 0.5 | 0.06 |
| Cefotaxime | >512 | 0.25 | 0.12 |
| Cefepime | >512 | 0.12 | 0.06 |
| Cefoxitin | >512 | 4 | 4 |
| Aztreonam | >512 | 0.12 | 0.12 |
| Imipenem | 0.12 | 0.06 | 0.06 |
a
MICs (μg/ml) of β-lactams for the A. johnsonii 7037 clinical isolate, E. coli DH10B harboring recombinant plasmid p7037-B2 expressing ß-lactamase SCO-1, and the E. coli DH10B reference strain.
b
CLA, clavulanic acid at a fixed concentration of 4 μg/ml; TZB, tazobactam at a fixed concentration of 4 μg/ml.