Table 2. Lipinski’s rule of five calculated by Molinspiration.

Molecule	MiLogp	Mw	H acceptor	H donor	Violations
Y-3	-0.719	359.337	9	2	0
1	0.906	481.504	10	1	0
2	1.131	493.515	10	0	0
3	1.317	489.527	9	0	0
4	-0.103	453.45	10	0	0
5	-0.799	498.491	12	2	1
6	1.196	489.527	9	0	0
7	-0.188	465.461	10	0	0
8	-0.374	496.475	12	1	1
9	0.858	481.504	10	0	0
10	0.979	455.466	10	0	0
11	1.137	479.488	10	0	0
12	-1.764	483.436	13	1	1
13	0.293	467.477	10	0	0
14	0.948	495.531	10	0	0
15	-0.574	467.433	11	1	1
16	-0.558	468.465	11	1	1
17	1.324	481.504	10	0	0
18	0.672	479.488	10	0	0
19	-0.762	498.447	13	2	1
20	-0.857	482.492	11	1	1
21	1.136	489.483	10	0	0