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. 2006 Dec 23;1(8):314–320. doi: 10.6026/97320630001314

Table 1. Some enzymes as drug targets.

Enzyme Drug
Dihydrofolate reductase Methotrexate
HIV-1 protease Saquinavir, Indinavir
ACE Captopril
Neuraminidase Oseltamivir
Cyclin dependent Kinase(CDKs) Flavopiridol
Cyclooxygenase Diclofenac, Indomethacin
Thymidylate synthase Tomudex
Guanine phosphoribosyltranseferase (GPRT) Allopurinol
Inosine5'-monophosphate dehydrogense Tiazopurin