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Serum Concentrations of Warfarin, Prothrombin Time, and Hematocrit of Thy1 Rats Treated with Warfarin
| Warfarin concentration in drinking water (mg/l) | 0 | 0.25 | 0.5 |
|---|---|---|---|
| Serum warfarin concentration (μmol/L) | 0 | 0.28 ± 0.05* | 1.23 ± 0.4* |
| Prothrombin time (seconds) | 12.63 ± 0.51 | 13.33 ± 0.28 | 14.10 ± 1.49 |
| Hematocrit (%) | 48.4 ± 1.0 | 49.6 ± 1.2 | 47.4 ± 1.9 |
Data are expressed as means ± SD (n = 6 for each group).
*P < 0.001 versus nontreated Thy1 rats.
