Table 2.
Genes Up-Regulated in Advanced Stage 2A as Compared to Earlier Stage Pb1 Lymphoma Cells
| Genes | Fold increase |
|---|---|
| Group A (genes involved in cell signaling) | |
| Interleukin-6* | 20 |
| Midkine | 6 |
| Platelet-derived growth factor beta chain | 6 |
| Interleukin-1 receptor, type II* | 24 |
| Erythropoietin receptor | 22 |
| Cell surface glycoprotein A15/Talla* | 19 |
| Grancalcin* | 6 |
| Tyrosine-protein kinase CAK* | 9 |
| Transcription factor BTF3* | 6 |
| Transcription factor SATB1* | 5 |
| Zinc finger protein IA-1 | 8 |
| Group B (genes involved in drug resistance) | |
| Bleomycin hydrolase gene* | 13 |
| Na/taurocholate cotransporting polypeptide | 23 |
| Group C (miscellaneous) | |
| Cytochrome c oxidase subunit Vb | 29 |
| Glucosamine-6-phosphate isomerase | 6 |
| Hemoglobin epsilon | 11 |
| CD83 | 6 |
| Myelin basic protein* | 5 |
| Alpha-1-antitrypsin* | 50 |
| Tissue plasminogen activator | 28 |
| Profilin II | 7 |
| Heparin cofactor II | 10 |
*Identity of the clones as defined by the provider was additionally confirmed by us by re-sequencing