Table 3.

Genes Down-Regulated in Advanced Stage 2A Compared to Earlier Stage PB1 Lymphoma Cells

Genes	Fold decrease
Group A (putative inhibitiors of cell signaling)
Protein tyrosine phosphatase 1C*	8
Protein tyrosine phosphatase gamma*	5
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2	11
Protein tyrosine phosphatase (tissue type: foreskin)	17
cAMP-dependent 3′,5′-cyclic phosphodiesterase 4*	5
CD45*	10
Group B (mediators of cell adhesion)
Fibronectin receptor beta subunit*	5
Laminin gamma-1 chain*	9
Leukocyte adhesion glycoprotein LFA-1 alpha chain*	13
Vascular cell adhesion protein-1	14
Platelet endothelial cell adhesion molecule	11
Cadherin 5	6
Thrombin receptor*	15
Testican	26
Group C (genes involved in DNA repair and cell apoptosis)
Ataxia-telangiectaxia group-D-associated protein*	23
D4-GTPase dissociation inhibitor protein*	63
Annexin I	7
TNF-related apoptosis inducing ligand TRAIL*	9
Granzyme H*	11
Guanine nucleotide regulatory protein (nep1)*	9
Cathepsin L*	6
Glutaredoxin*	10
Group D (negative regulator of cell cycle progression)
P16 (cyclin-dependent kinases regulatory subunit 1)	5
Group E (miscellaneous)
T-cell receptor alpha chain*	20
Natural Killer cell G7 protein*	12
Human (2′-5′) oligo A synthetase E	7
Thromboxane A synthase*	6
Complement factor H*	6
Tonsillar lymphocyte LD78 beta protein*	8
Macrophage capping protein	8
Low-density lipoprotein receptor	9
Mac-2 binding protein*	9
Ankyrin G	9
Drebrin E	10
FLI-1 oncogene*	10
Beta-2 adrenergic receptor*	13
Interferon-induced guanylate-binding protein-1	17
Antileukoproteinase-1*	16
Glia-derived nexin*	20
Guanine nucleotide-binding protein alpha- 16 subunit*	19
Placental calcium-binding protein	24

*Identify of the clones as defined by the provider was additionally confirmed by us by resequencing.