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Cytokine production by cultured type-1 (PPD) and type-2 (SEA) Ag-bead lung granulomas. Granulomas were isolated from the lungs (four to five mice per point) and cultured for 48 hours in the presence of either PPD or SEA (5 μg/ml). Supernates were collected and assayed for the indicated cytokines. Bars are means ± SE.
