Table 2.
Results of Whole-Tissue DNA Analysis and MHC Class II Typing in AILD
| Case | TCRβ PCR whole tissue | TCRγ† whole tissue | IgH† whole tissue | MHC II | ||
|---|---|---|---|---|---|---|
| DRB1* | DQB1* | DPB1* | ||||
| 1 | Clonal | Clonal | Polyclonal | 03, 07 | 02, 0302 | 0101, 0401 |
| 2 | Clonal | Clonal | Polyclonal | 03, 13 | 02, 06 | 0301, 0401 |
| 3 | Clonal | Clonal | Polyclonal | 11, 16 | 0301, 05 | 0201, 0401 |
| 4 | Polyclonal | Polyclonal | Polyclonal | 01, 07 | 05, 02 | nd |
| 5 | Polyclonal | Clonal | Polyclonal | 10, 13 | 05, 06 | 0201, 0402 |
| 6 | Polyclonal | Polyclonal | Polyclonal | 13, 13 | 06, 06 | nd |
| 7 | Polyclonal | Polyclonal | Polyclonal | 15, − | 06,− | nd |
| 8 | Clonal | nd | nd | nd | nd | nd |
| 9 | Polyclonal | nd | nd | nd | nd | nd |
| 10 | Clonal | nd | nd | nd | nd | nd |
| 11 | Clonal | nd | nd | nd | nd | nd |
| 12 | Polyclonal | nd | nd | nd | nd | nd |
| 13 | Polyclonal | Clonal | Polyclonal | 03, 11 | 02, 0301 | nd |
| 14 | Clonal | Clonal | Polyclonal | 14, − | 15,− | nd |
| 15 | Clonal | Clonal | Clonal | 11, 13 | 06, 0301 | nd |
| 16 | Clonal | Clonal | Polyclonal | 11, 15 | 06, 0301 | 0401, 0402 |
| 17 | Polyclonal | Polyclonal | Polyclonal | 11, − | 02, 0301 | nd |
| 18 | Clonal | Clonal | Polyclonal | 01, 13 | 05, 06 | 0401, 0402 |
†CDR3 length distribution analysis of IgH and TCRγ gene rearrangements.