Table 2.
Characteristics of the Three Primary Neuroblastoma Tumors Irradiated
Tumor identity | Age of patient (yr) | Stage | Genetics | p53 status | Histology* | p53 DO-7 LI % | p53 DO-1 LI % | p53 1801 LI % | Ki67 LI % |
---|---|---|---|---|---|---|---|---|---|
1 | 2 | 1 | Non-MYCN amplified | WT | >5% Differentiating, stroma poor, calcification (favorable) | 3 | 3 | 0 | 13 |
2 | 2 | 4 | MYCN amplified, 1p deleted | WT | Poorly differentiated, high MKI, stroma poor (unfavorable) | 74 | 33 | 9 | 86 |
3 | 2 | 4 | Non-MYCN amplified | WT | Ganglioneuroblastoma, nodular (unfavorable), stroma rich part studied | 3 | 1 | <1 | 15 |
*International Neuroblastoma Pathology Classification.
LI, labeling index; WT, wild type; MKI, mitosis karyorrhexis index.