Skip to main content
. 2007 May 29;8:18. doi: 10.1186/1471-2121-8-18

Table 1.

Percentage of CpG methylation in the LEP, PPARG2, FABP4 and LPL promoters in undifferentiated and differentiated ASC clones at passage 4 (P4) and at senescence (Ps)

Percent methylated cytosines in promoter region examined

Gene LEP PPARG2 FABP4 LPL
Passage No. P4 Ps P4 Ps P4 Ps P4 Ps

Undifferentiated
ASC clone B1 9 17a 10 20c 15 45a 20 8a
B2 7 14a 15 18ns 30 25ns 27 26ns
B3 24 24ns 29 23ns 50 75a 19 19ns

Differentiated
ASC clone B1 13 13ns 5 33a 12 13ns 17 11ns
B2 4 17a 17 25c 22 25ns 29 24ns
B3 22 38a 17 22ns 50 70b 18 14ns

Chi-square tests: a P < 0.001; b P < 0.005; c P < 0.05; ns non-significant.