Table 1.
Median doses to the left anterior descending coronary artery (LAD) in [Gy] for 3 differently sized target volumes
| Maximum dose (range)* | Median dose (range) | Median volume receiving 100% | Median volume receiving 25%* | |
| Small, AP-PA | 28.5 Gy (27.3–29.4) | 23.4 Gy (18.3–27.0) | 0% (0-0) | 69% (65–80) |
| Small, 4-field | 29.7 Gy (28.5–30.0) | 21.3 Gy (13.2–26.1) | 0% (0-0) | 72% (56–80) |
| Small, IMRT | 28.5 Gy (21.3–29.7) | 11.1 Gy (8.7–14.1) | 0% (0-0) | 70% (53–75) |
| Intermediate, AP-PA | 30.6 Gy (30.0–31.2) | 30.0 Gy (26.4–30.0) | 50% (1–82) | 98% (74–100) |
| Intermediate, 4-field | 30.6 Gy (30.0–30.9) | 29.0 Gy (19.2–30.3) | 23% (0–93) | 100% (89–100) |
| Intermediate, IMRT | 26.9 Gy (23.7–30.0) | 15.9 Gy (10.8–29.4) | 0.25% (0–26) | 92% (78–100) |
| Large, AP-PA | 31.5 Gy (29.7–31.8) | 30.5 Gy (30.2–30.6) | 90% (60–98) | 100% (100-100) |
| Large, 4-field | 31.2 Gy (30.6–31.8) | 28.5 Gy (21.9–29.4) | 23% (18–25) | 100% (100-100) |
| Large, IMRT | 29.1 Gy (27.3–31.2) | 15.9 Gy (15.0–21.9) | 3% (0–9) | 88% (82–95) |
* Statistical testing was not performed for these parameters.
p < 0.01 for comparison of the median LAD dose with ap-pa vs. IMRT and 4-field vs. IMRT.
p < 0.01 for comparison of the median volume receiving 100% with ap-pa vs. both 4-field and IMRT (for both intermediate and large PTV). The differences between 4-field and IMRT are also statistically significant.
Small volume: upper mediastinal plus paraclavicular nodal areas (566–860 ccm), intermediate volume: lower mediastinal nodes in addition (774–1337 ccm), large volume: hilar nodes in addition (936–1664 ccm)