Table 6.

Filtering cutoffs for removing redundancy in the testing sets.

	Initial set	Sequence Identity (%)	Equivalent positions (%)	RMSD (Å)	Difference in length	Final set
Annotation	10,997	N/A	≥60.0	≤2.0	≤30	1,879
Ligand	30,126	≥30.0	≥75.0	≤4.0	≤50	4,948
Partner	30,425	≥30.0	≥75.0	≤4.0	≤50	4,613
Localize	30,126	≥90.0	≥90.0	≤2.0	N/A	1,936

Sequence identity is the percentage of identical residues with respect to the aligned positions in the structural alignment. Equivalent position is the percentage of residues that align within 4 Å with respect to the shorter of the two aligned structures. The RMSD is calculated using Cα atoms of the two aligned structures.