Table 3.
Dietary mutagen intake and mutagenic activity index in cases and controls
| Variable | Cases (N = 626) | Controls (N = 530) | P value* |
|---|---|---|---|
| MeIQx(ng/day) | |||
| Mean ± SD | 68.4 ± 92.2 | 55.8 ± 71.9 | 0.13 |
| Median (range) | 38.6 (16.3-82.3) | 32.6 (16.4-65.9) | 0.07 |
| DiMeIQx(ng/day) | |||
| Mean ± SD | 4.2 ± 7.0 | 2.9 ± 4.1 | 0.01 |
| Median (range) | 2.0 (0.7-4.8) | 1.8 (0.6-3.6) | 0.02 |
| PhIP (ng/day) | |||
| Mean ± SD | 236.3 ± 448.4 | 203.5 ± 285.2 | 0.27 |
| Median (range) | 126.4 (58.0-283.7) | 118.4 (50.5-251.5) | 0.20 |
| BaP (ng/day) | |||
| Mean ± SD | 69.9 ± 92.5 | 61.2 ± 74.9 | 0.64 |
| Median (range) | 42.3 (11.6-91.8) | 37.3 (11.6-77.9) | 0.19 |
| Mutagenicity (revertants/g/day) | |||
| Mean ± SD | 10,658.5 ± 18,445.3 | 8,108.1 ± 8,948.5 | 0.14 |
| Median (range) | 6,000.1 (2,997.9-11,933.8) | 5,465.2 (2,926.1-9,971.6) | 0.07 |
| Calories (kcal) | |||
| Mean ± SD | 1,879.6 ± 851.2 | 1,948.4 ± 738.7 | 0.21 |
| Median (range) | 1,789.0 (1,380.9-2,375.8) | 1,760.5 (1,378.4-2,258.9) | 0.47 |
| Protein (g) | |||
| Mean ± SD | 85.5 ± 38.9 | 83.7 ± 36.3 | 0.48 |
| Median (range) | 78.9 (60.3-101.7) | 78.3 (58.7-101.4) | 0.60 |
| Animal fat (g) | |||
| Mean ± SD | 40.9 ± 24.1 | 38.8 ± 20.7 | 0.17 |
| Median (range) | 36.4 (25.9-50.9) | 34.0 (24.1-49.2) | 0.18 |
| Total fat (g) | |||
| Mean ± SD | 74.0 ± 37.4 | 74.0 ± 34.2 | 1.00 |
| Median (range) | 65.9 (50.2-91.3) | 68.0 (49.8-90.9) | 0.68 |
*
P values for comparison of the means were from ANOVA of natural log-transformed HCA, BaP, and mutagenicity values. P values for comparison of the medians were from Mann-Whitney test.